Serological and demographic survey of Epstein-Barr virus infection in Ethiopia
Identifieur interne : 001591 ( Main/Exploration ); précédent : 001590; suivant : 001592Serological and demographic survey of Epstein-Barr virus infection in Ethiopia
Auteurs : E. Tsega [Éthiopie] ; B. Mengesha [Éthiopie] ; B.-G. Hansson [Éthiopie] ; E. Nordenfelt [Éthiopie] ; J. Lindberg [Éthiopie]Source :
- Transactions of the Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 1987.
Descripteurs français
- Wicri :
- geographic : Éthiopie.
- topic : Distribution de l'eau.
English descriptors
- KwdEn :
- Ababa, Addis, Addis ababa, Addis ababa university, Antibody positivity, Antibody test, Blood transfusions, Carcinoma, Central africa, Clinical data, Demographic survey, Different parts, Different provinces, Early exposure, Economic status, Ethiopia, Excreta disposal, Family size, Heterophile antibodies, Heterophile antibody, High rate, International livestock centre, Liver diseases, Lymphoma, Nasopharyngeal, Nasopharyngeal carcinoma, Parenteral exposure, Serological survey, Virus infection, Water supply, West africa, Young adult ethiopians.
- Teeft :
- Ababa, Addis, Addis ababa, Addis ababa university, Antibody positivity, Antibody test, Blood transfusions, Carcinoma, Central africa, Clinical data, Demographic survey, Different parts, Different provinces, Early exposure, Economic status, Ethiopia, Excreta disposal, Family size, Heterophile antibodies, Heterophile antibody, High rate, International livestock centre, Liver diseases, Lymphoma, Nasopharyngeal, Nasopharyngeal carcinoma, Parenteral exposure, Serological survey, Virus infection, Water supply, West africa, Young adult ethiopians.
Abstract
A demographic and serological survey of Epstein-Barr virus infection was carried out in 5 geographically representative regions of Ethiopia. 80% of the 500 people studied were under 15 years of age. 82% of children under 5 years of age and 94% under 10 years of age were positive for IgG anti-viral capsid antigen (VCA) antibody. 51 of 100 children under 12 months of age and from 5 different provinces were positive for anti-VCA antibody. Of these, 23 were under 6 months. The distribution of anti-VCA antibody positivity was comparable in both sexes, in each age group and in the different provinces at different altitudes. Economic status, expressed in terms of estimated income, type of water supply, mode of excreta disposal and family size, did not significantly influence the distribution of anti-VCA antibody. Thus, early exposure to Epstein-Barr virus, with asymptomatic or subclinical presentation, probably accounts for the rarity of typical infectious mononucleosis in young adult Ethiopians. The lack of a relationship between Epstein-Barr virus infection and Burkitt's lymphoma, nasopharyngeal carcinoma, malaria as well as liver diseases is briefly discussed.
Url:
DOI: 10.1016/0035-9203(87)90452-4
Affiliations:
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Of these, 23 were under 6 months. The distribution of anti-VCA antibody positivity was comparable in both sexes, in each age group and in the different provinces at different altitudes. Economic status, expressed in terms of estimated income, type of water supply, mode of excreta disposal and family size, did not significantly influence the distribution of anti-VCA antibody. Thus, early exposure to Epstein-Barr virus, with asymptomatic or subclinical presentation, probably accounts for the rarity of typical infectious mononucleosis in young adult Ethiopians. The lack of a relationship between Epstein-Barr virus infection and Burkitt's lymphoma, nasopharyngeal carcinoma, malaria as well as liver diseases is briefly discussed.</div></front></TEI><affiliations><list><country><li>Éthiopie</li></country></list><tree><country name="Éthiopie"><noRegion><name sortKey="Tsega, E" sort="Tsega, E" uniqKey="Tsega E" first="E." last="Tsega">E. 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